Muscular Dystrophies

Muscular dystrophies are a group of genetic disorders that lead to muscle weakness and progressive muscle degeneration.

Key types of muscular dystrophy include:

Becker Muscular Dystrophy (BMD): A milder and later-onset form compared to Duchenne, BMD causes progressive muscle weakness.

Congenital Muscular Dystrophy: This type manifests at birth or within the first two years and is often associated with various genetic mutations.

Duchenne Muscular Dystrophy (DMD): The most common and severe form of muscular dystrophy, predominantly affecting boys and beginning in early childhood, leading to muscle wasting and weakness.

Facioscapulohumeral Muscular Dystrophy (FSHD): This form affects the face, shoulders, and upper arms, often starting in late childhood or adolescence.

Other limb girdle muscular dystrophies (LGMDS)

Management and Treatment

Management strategies for myopathies vary depending on the specific type and severity of the condition:

Physical therapy: Customized exercise programs help maintain muscle function, strength, and mobility.

Medications: Anti-inflammatory drugs or immunosuppressants can treat autoimmune-related myopathies such as polymyositis and dermatomyositis.

Medication adjustments: In cases of statin-associated myopathies, discontinuing or adjusting statin dosage may be necessary to alleviate symptoms.

Assistive devices: Braces, wheelchairs, or other mobility aids can support independence and daily functioning.

Surgical interventions: Surgery may be considered in some cases for musculoskeletal deformities or contractures.

Lifestyle modifications: Diet, exercise, and stress management can help optimize health and manage symptoms.

Ongoing research continues to explore novel treatments and therapies for myopathies, providing hope for improved management and outcomes for affected individuals. Early diagnosis and intervention can lead to better symptom control and quality of life.